To our knowledge, a comparative study of blood serumexosome isolation
methods for miRNA profiling has not been conducted. Therefore,
the aim of our study was to determine whether the exosomal miRNA
profile in serum samples depends on exosome isolation method. In
this study, miRNA content fromexosomes obtained by a “gold standard”
ultracentrifugation based method and ExoQuick Precipitation Solution
was compared.