Several mushroom species have been pointed out as sources of antioxidant compounds, in addition totheir important nutritional value. Agaricus blazei and Lentinus edodes are among the most studied speciesall over the world, but those studies focused on their fruiting bodies instead of other presentations, suchas powdered preparations, used as supplements. In the present work the chemical composition (nutrientsand bioactive compounds) and antioxidant activity (free radical scavenging activity, reducing power andlipid peroxidation inhibition) of dried powder formulations of the mentioned mushroom species (APF andLPF, respectively) were evaluated. Powder formulations of both species revealed the presence of essentialnutrients, such as proteins, carbohydrates and unsaturated fatty acids. Furthermore, they present a lowfat content (<2 g/100 g) and can be used in low-calorie diets, just like the mushrooms fruiting bodies. APFshowed higher antioxidant activity and higher content of tocopherols and phenolic compounds (124 and770 lg/100 g, respectively) than LPF (32 and 690 lg/100 g). Both formulations could be used as antioxidantsources to prevent diseases related to oxidative stress
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