The incorporation of astaxanthin in nanodispersion systems is a
promising alternative to the use of water-insoluble astaxanthin in water-based food systems. The results of this research confirmed the dependency of the chemical stability of astaxanthin nanodispersions on the selected food systems. The results also confirmed that the nature of the stabiliser used and the dilution factor have considerable effects on the stability of astaxanthin in prepared nanodispersion systems. The in vitro cellular uptake measurements also demonstrated that the astaxanthin was more bioavailable when nanodispersions of astaxanthin were used in food systems with protein or dietary fat ingredients such as milk. Therefore, because the selected food system can affect the bioavailability of astaxanthin significantly, further research is needed to study and quantify the effects of various food ingredients on the bioavailability of bioactive compounds in nanodispersion systems.