YSTEMIC SKIN WHITENING AGENTS AVAILABLE IN THE SYSTEMIC SKIN WHITENING AGENTS AVAILABLE IN THE MARKET MARKET
GSH The most commonly used systemic skin whitening agent is GSH used alone or in various combinations, both as oral and intravenous formulations. GSH is an antioxidant synthesized in all mammalian cells from three amino acids-glutamate, cysteine, and glycine. It is also available naturally in watermelon, avocado, broccoli, spinach and tomatoes. GSH exists in cells mostly in the reduced form (GSH) which is constantly oxidized forming oxidized GSH and its supply is replenished by the action of GSH reductase. GSH is involved in various biochemical processes especially those involving scavenging of free radicals and detoxification of toxic compounds, it acts as coenzyme and helps in the transport of amino acids across the cell membranes.[1] Lower GSH levels are implicated in many diseases and GSH