Exergy-topological analysis is applied to a binary medium-grade geothermal power plant. The analysis shows that the power plant can operate at high thermodynamic efficiency without using high- cost advanced powerfluids. The boiler is found to posses the highest coefficient of influence in the conventional regenerative system. Pumps (including those used in the cycles for geothermal fluid and cooling water) and the feed-water heater are identified as minor components. The condenser is found to be the critical component with the highest rate of exergy loss. Decreasing condenser pressure, while extracting fluid at a specific pressure for feed-water heating, is found to be a key strategy for improving thermodynamic effi- ciency of the medium-grade geothermal power plant.