It is interesting to note that direct correlation
between anabolism and catabolism enzymes activity (TK,
TP) and age was revealed. This mechanism can regulate
the velocity of their pathway of dTTP synthesis in healthy
organism. The ADA and 5’-NT activities get the highest
values at the age 36–45 years. A strong positive correlation
between the two enzyme activities has been demonstrated
( = 0,746). So ADA and 5’-NT have cooperative effect
on the adenosine levels in human organism.