The synthesis of nanophase hydroxyapatite (nHA) is of importance in the field of
biomaterials and bone tissue engineering. The bioactive and osteoconductive
properties of nHA are of much benefit to a wide range of biomedical applications
such as producing bone tissue engineered constructs, coating medical implants or as a
carrier for plasmid DNA in gene delivery. This study aimed to develop a novel lowtemperature dispersant-aided precipitation reaction to produce nHA particles (