Next we examined if traumatic brain injury among relatives was correlated to their degree of relationship to the proband. A correlation might be expected if a history of traumatic brain injury among relatives was related to genetic vulnerability and if the probands had the highest level of genetic vulnerability among their relatives. The association between traumatic brain injury and degree of relationship to the proband approached statistical significance in the schizophrenia pedigree (χ2=8.89, df=4, p<0.07), but was not significant in the bipolar pedigree group (χ2=5.57, df=4, p=0.23).
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