The diabetic rats were marked conveniently and randomly distributed into four groups of 6 animals each. All the animals were over night fasted with water ad libitum. The animals in group-1 received 2% w/v acacia suspension and the animals in the group- 2 received rabeprazole (40 mg/kg, p.o) in acacia suspension. Group-3 received glibenclamide (200 μg/kg, p.o) and group-4