Moreover, using black cumin oil significantly enhanced
the immune system through increased lymphocyte production,
and inhibited development of advanced dysplastic changes
after topical application of DMBA (7,12-Dimethylbenz(a)
anthracene) in hamsters to induce immune-suppression
(Al-Jawfi et al., 2008). However, the total immunoglobulin
levels were significantly (P < 0.05) higher than those of the
control group when fed BCS based on that finding and the
low cost of BCS addition with immune-simulative effect of
BCS, Dorucu et al. (2009) recommended its use in fish feed
to reduce mortalities caused by some pathogens. The present
results disagreed with the finding of (Jang, 2011) who recorded
no significant effects on immunity parameters except in heterophile:
lymphocyte ratio.