Wood vinegar or pyroligneous acid is a brown transparent liquid that produced by the condensation of the smoke from wood burning in airless condition. Wood vinegar has been used in agriculture as plant growth regulator, insect repellent and fertilizer. The effect of wood vinegar and farm yard manure on growth and yield of KDML 105 rice was investigated in RCBD with 3 replications experimental design. Treatments were consisted of 1) with out application of wood vinegar and manure (control) 2) application of wood vinegar + chicken manure 300 kg/rai 3) application of wood vinegar + chicken manure 600 kg/rai 4) application of wood vinegar + cattle manure 500 kg/rai 5) application of wood vinegar + cattle manure 1,000 kg/rai, when the second to the fifth treatments were treatments that the ratio of wood vinegar per water is 1:300 were applied as foliar application at 15 days interval, until 7 days before harvest. Fertilizer was applied 10 days before transplanting. Top dressing was made at flowering stage on the second and the third treatment at the rate of 100 kg/rai for chicken manure and on the forth and the fifth treatment at the rate of 200 kg/rai for cattle manure. The experiment was conducted on farmer's field at Ban Tum, Muang Dustrict, Khon Kaen Province between May-November 2006. The results showed that at tillering stage, the foliar application of wood vinegar with 300 or 600 kg/rai of chicken manure significantly increased tiller number.