The mean anxiety score before venipuncture in control, bubble making, and regular breathing exercise groups was 31.7, 30.78, and 29 respectively. After venipuncture, the mean anxiety score was 41.50, 29.45 and 20.55, respectively. These findings indicated a significant difference in the mean anxiety scores between the three studied groups after the venipuncture. However, there was no significant difference between the mean anxiety score in the two distraction groups (bubble making and regular breathing exercise).