An important advance in the study of aneuploidy was the discovery that many cancer cell lines exhibit chromosomal instability, a phenotype in which cell division is accompanied by an abnormally high rate of chromosome loss and gain [19].
Animportant advance in the study of aneuploidy was thediscovery that many cancer cell lines exhibit chromosomalinstability, a phenotype in which cell division isaccompanied by an abnormally high rate of chromosomeloss and gain [19].