littermates only containing the floxed BDNF allele were all tested in our behavioral paradigms and no phenotypic difference was observed between these various control groups. Since there were no phenotypic differences between these groups, these three groups were combined to generate the wildtype (WT) littermate control mice of the BDNF conditional KO mice. Prior to all testing, mice were allowed to habituate in the behavioral room for 1 hour. For all experiments, significance was p .05.