The results of the analysis of messenger RNA (mRNA) expression of CYP1A1 gene as shown in Figure 1(a) indicated that it was not significantly affected in the pesticide-exposed individuals when compared with healthy controls. The expression profile
of a housekeeping gene, GAPDH, has been used as a reference. The band density ratio of CYP1A1 to that of GAPDH presented in Figure 1(b) illustrates the similar pattern. In contrast, the levels of mRNA expression of CYP2E1 and GST-pi genes were observed to be increased in the pesticide-exposed individuals when compared with healthy control. The CYP2E1 mRNA expression is found to be significantly increased in comparison with the control (Figure 2(a)). The band density ratio of CYP2E1 to that of GAPDH presented in Figure 2(b) also reflects the similar effect. GST-pi mRNA expression is also more in the WBCs of pesticide-exposed individuals than the normal controls (Figure 3(a)). The band density ratio of GST-pi to that of GAPDH presented in Figure 3(b) also corroborate this increasing expression pattern of GST-pi gene in occupationally pesticide-exposed individuals.