The major strength of our analysis is its multicenter
nature, which provided a large number of participants
frommany countries and captured all traveler types, and
its focus on proportionate morbidity. The limitations
of this method of analysis have been recently
discussed.
32
In particular, because the denominator
data (number of travelers) cannot be ascertained, it
is not possible to calculate incidence rates or absolute
risk. Also, this data might not be representative of
the overall population of travelers, and the results
do not represent the broad spectrum of illnesses
typically seen at non-specialized primary care practices
where mild or self-limited conditions present with
higher frequency. Due to the nature of GeoSentinel
clinics, illnesses acquired after travel to non-tropical
destinations or non-infectious travel-related illnesses
may be underrepresented. Underlying chronic diseases
are not documented by GeoSentinel which does not
allow evaluation of their influence on travel-associated
morbidity. However, the GeoSentinel database (and
The major strength of our analysis is its multicenter
nature, which provided a large number of participants
frommany countries and captured all traveler types, and
its focus on proportionate morbidity. The limitations
of this method of analysis have been recently
discussed.
32
In particular, because the denominator
data (number of travelers) cannot be ascertained, it
is not possible to calculate incidence rates or absolute
risk. Also, this data might not be representative of
the overall population of travelers, and the results
do not represent the broad spectrum of illnesses
typically seen at non-specialized primary care practices
where mild or self-limited conditions present with
higher frequency. Due to the nature of GeoSentinel
clinics, illnesses acquired after travel to non-tropical
destinations or non-infectious travel-related illnesses
may be underrepresented. Underlying chronic diseases
are not documented by GeoSentinel which does not
allow evaluation of their influence on travel-associated
morbidity. However, the GeoSentinel database (and
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