(A-F) NuMA is relocalised in HSV-1-infected cells. HEp-2 cells were either mock-infected (A) or infected with HSV-1 at a MOI of 3 PFU/cell, fixed at 3 hours (B), 6 hours (C), 9 hours (D), 12 (E) and 15 hours (F) post infection, and then analysed for NuMA localisation. NuMA diminuition in the centre of the nucleus can be observed from 9 hours post infection (D). The percentage of cells exhibiting such nuclear localisation of NuMA (arrow in panel D) were quantified by examining at least 200 cells (given at bottom left within each panel).