DISCUSSION ((แฝดด)))
In our cohort of nulliparas who underwent labor induction, we found that almost 40% of women who remained in the latent phase after 12 hours of oxytocin with ruptured membranes were delivered vaginally. These data, prospectively collected from 14 centers, broaden our understanding of the benefits and risks of progressively longer latent-phase durations among nulliparas undergoing labor induction. They are consistent with two prior single-center investigations that showed progressively lower rates of vaginal delivery with longer durations of the latent phase, and higher rates of associated maternal infection, but no increase in neonatal morbidity rates.6,7 All three studies report outcomes with the same reproducible metric (duration of oxytocin administration after membrane rupture) and utilize a common definition of the latent phase, defined in terms of cervical dilation and effacement.
The first of the single center studies, by Rouse et al included 361 nulliparas who underwent labor induction with an unfavorable cervix at or beyond 36 weeks of gestation.6 Their overall cesarean delivery rate was 25%. In their study cohort, 13 of the 15 women (87%) who had not entered the active phase (cervical dilation of at least 4 cm and effacement at least 90% or cervical dilation at least 5 cm regardless of effacement) by 12 hours ultimately were delivered by cesarean, and 27% were diagnosed with chorioamnionitis. No other maternal or neonatal morbidities were correlated with the duration of the latent phase.
In the second single-center study, by Simon and Grobman, 397 nulliparas who underwent labor induction at 36 weeks of gestation or greater were evaluated.7 The overall cesarean delivery rate for these women was 26%. Only 19 women (5%) had latent-phase durations that exceeded 18 hours, and their cesarean delivery rate was 68%. However, two-thirds of the women with latent-phase durations of 15–18 hours were delivered vaginally, and vaginal delivery rates were even higher for women with shorter latent-phase
durations. In addition to chorioamnionitis, postpartum hemorrhage was correlated with latent-phase duration, but blood transfusion or other maternal or neonatal morbidities were not.
DISCUSSION ((แฝดด)))In our cohort of nulliparas who underwent labor induction, we found that almost 40% of women who remained in the latent phase after 12 hours of oxytocin with ruptured membranes were delivered vaginally. These data, prospectively collected from 14 centers, broaden our understanding of the benefits and risks of progressively longer latent-phase durations among nulliparas undergoing labor induction. They are consistent with two prior single-center investigations that showed progressively lower rates of vaginal delivery with longer durations of the latent phase, and higher rates of associated maternal infection, but no increase in neonatal morbidity rates.6,7 All three studies report outcomes with the same reproducible metric (duration of oxytocin administration after membrane rupture) and utilize a common definition of the latent phase, defined in terms of cervical dilation and effacement.The first of the single center studies, by Rouse et al included 361 nulliparas who underwent labor induction with an unfavorable cervix at or beyond 36 weeks of gestation.6 Their overall cesarean delivery rate was 25%. In their study cohort, 13 of the 15 women (87%) who had not entered the active phase (cervical dilation of at least 4 cm and effacement at least 90% or cervical dilation at least 5 cm regardless of effacement) by 12 hours ultimately were delivered by cesarean, and 27% were diagnosed with chorioamnionitis. No other maternal or neonatal morbidities were correlated with the duration of the latent phase.ในศึกษาศูนย์เดียวสอง โดย Simon และ Grobman, nulliparas 397 ที่รับแรงเหนี่ยวนำที่ 36 สัปดาห์ครรภ์ หรือมากกว่า ได้ evaluated.7 อัตราการจัดส่งโดยรวม cesarean สำหรับผู้หญิงเหล่านี้มี 26% ผู้หญิง 19 เท่า (5%) มีระยะเวลาแฝงอยู่ระยะที่เกิน 18 ชั่วโมง และอัตราการส่ง cesarean เป็น 68% อย่างไรก็ตาม มีส่งสองในสามของผู้หญิงที่ มีช่วงเวลาแฝงอยู่ระยะ 15-18 ชั่วโมง vaginally และคลอดราคาได้สูงสำหรับผู้หญิงที่มีสั้นแฝงอยู่เฟสระยะเวลาการ นอกจากถุงน้ำคร่ำอักเสบ ตกเลือดหลังคลอดถูก correlated กับระยะเวลาของระยะแฝงอยู่ แต่โลหิตหรือตัวอื่น ๆ แม่ หรือทารกแรกเกิดไม่
การแปล กรุณารอสักครู่..