In the control group on D3, macroscopically the lesion resembles macroscopically the experimental group. However, in D7 is slightly more moist and in D11 also showed a tendency of complete healing, but the presence of tissue with a little bleeding at the bottom of the ulcer could be observed, a fact which corroborates the findings of histopathology. This result can be attributed to the mechanical effect of the polysaccharide film.