ABSTRACT
Background
In patients with metastatic breast cancer that is positive for human epidermal
growth factor receptor 2 (HER2), progression-free survival was significantly improved
after first-line therapy with pertuzumab, trastuzumab, and docetaxel, as
compared with placebo, trastuzumab, and docetaxel. Overall survival was significantly
improved with pertuzumab in an interim analysis without the median being
reached. We report final prespecified overall survival results with a median followup
of 50 months.
ABSTRACTBackgroundIn patients with metastatic breast cancer that is positive for human epidermalgrowth factor receptor 2 (HER2), progression-free survival was significantly improvedafter first-line therapy with pertuzumab, trastuzumab, and docetaxel, ascompared with placebo, trastuzumab, and docetaxel. Overall survival was significantlyimproved with pertuzumab in an interim analysis without the median beingreached. We report final prespecified overall survival results with a median followupof 50 months.
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