Yi-Hung Chen and colleagues (2010) studied the production of bio-diesel continuous use Rotating packed bed is found that the optimal ratio of soybean oil with methanol is 6: 1 Residence time 0.72 minutes and speed. 900 rounds per minute at a temperature of 42-60 degrees Celsius, making the Yield of fatty acid methyl esters (YFAME) has a maximum value of 97.3 percent and Yield esters in fatty acid methyl (PFAME) values. up to 0.828 mol per minute