Case 2
A 59-year-old man with a history of drinking
alcohol in the past 3 days was admitted to the emergency
department of the regional hospital because
of progressive headache and visual disturbances. During
the initial assessment, he had cardiac arrest, and
cardiopulmonary resuscitation was performed successfully.
A CT scan of the brain showed no abnormalities,
but laboratory findings showed severe metabolic
acidosis with a pH o 6.59 and a base excess of -35.1.
Toxicology screening for common drugs, including
alcohols, was performed, but no toxic substances were
detected. The patient was admitted to the ICU, and
hemodialysis was started immediately because of severe
metabolic acidosis. The patient’s condition deteriorated
rapidly, even during hemodialysis, and bilateral
mydriasis and brain stem unresponsiveness developed.
The brain CT was repeated, and severe brain swelling
was found. He was transferred to our department for
diagnosis of brain death and consideration for organ
donation. The patient was not registered in the National
Registry of Organ Donation Refusal, the family was
fully informed, and brain death was properly diagnosed.
A consultant from the Center of Transplantations
indicated donation of kidneys only. The patient
remained hemodynamically stable, and normal urine
output was maintained until organ procurement. The
last level of creatinine in the blood was 1.13 mg/dL,
and the acid base status was fully corrected to a pH of
7.39. A biopsy of the kidney was performed during
the procurement and showed normal kidney tissue
(Remuzzi score 0).
Retrospective toxicological analysis of the first
blood samples obtained revealed formic acid levels of
475 mg/L. Analysis of the blood obtained during
autopsy revealed no formic acid.
Case 2
A 59-year-old man with a history of drinking
alcohol in the past 3 days was admitted to the emergency
department of the regional hospital because
of progressive headache and visual disturbances. During
the initial assessment, he had cardiac arrest, and
cardiopulmonary resuscitation was performed successfully.
A CT scan of the brain showed no abnormalities,
but laboratory findings showed severe metabolic
acidosis with a pH o 6.59 and a base excess of -35.1.
Toxicology screening for common drugs, including
alcohols, was performed, but no toxic substances were
detected. The patient was admitted to the ICU, and
hemodialysis was started immediately because of severe
metabolic acidosis. The patient’s condition deteriorated
rapidly, even during hemodialysis, and bilateral
mydriasis and brain stem unresponsiveness developed.
The brain CT was repeated, and severe brain swelling
was found. He was transferred to our department for
diagnosis of brain death and consideration for organ
donation. The patient was not registered in the National
Registry of Organ Donation Refusal, the family was
fully informed, and brain death was properly diagnosed.
A consultant from the Center of Transplantations
indicated donation of kidneys only. The patient
remained hemodynamically stable, and normal urine
output was maintained until organ procurement. The
last level of creatinine in the blood was 1.13 mg/dL,
and the acid base status was fully corrected to a pH of
7.39. A biopsy of the kidney was performed during
the procurement and showed normal kidney tissue
(Remuzzi score 0).
Retrospective toxicological analysis of the first
blood samples obtained revealed formic acid levels of
475 mg/L. Analysis of the blood obtained during
autopsy revealed no formic acid.
การแปล กรุณารอสักครู่..
