Allergic-like
Diffuse edema, or facial edema with dyspnea
Diffuse erythema with hypotension
Laryngeal edema with stridor and/or hypoxia
Wheezing / bronchospasm, significant hypoxia
Anaphylactic shock (hypotension + tachycardia)
Physiologic
Vasovagal reaction resistant to treatment
Arrhythmia
Convulsions, seizures
Hypertensive emergency