Two separate instruments were used as part of the interview questionnaire to measure general and cancer-specific aspects of QOL. The PROMIS Global Health short form is a 10-item general QOL instrument assessing multiple domains. It has been validated in several studies including patients with chronic disease.[9], [10] and [11] PROMIS has two component scales: Global Physical Health (Promis Physical) and Global Mental Health (Promis Mental) which are scored separately. Higher scores represent better functioning. Raw scores range from 4 to 20 and were subsequently converted to T score values using published methodology. T score distributions are standardized such that a score of 50 represents the mean for the US general population, and the standard deviation around that mean is 10 points. T scores range from 16.2 to 67.7 again with higher scores representing better functioning.12 The scales have internal consistency reliability coefficients of 0.81 and 0.86 for physical and mental components, respectively.