An in vitro antiviral potential of the herbal medicinal product
Sinupret®, widely used in phytotherapeutical treatment of
acute and chronic rhinosinusitis, common cold and infections of
the upper respiratory tract has been observed by Glatthaar and
Christoffel (1998). The authors could show that Sinupret® drops
and 2 of 5 extracts that constitute the combination, i.e. extracts
of Verbena herb and Primula flower, reduced the spreading of
three viruses (influenza A, respiratory syncytial virus and parainfluenza
type 1). An antiviral effect of Sinupret® in vivo could be
demonstrated in a murine virus model (Sendai virus), in which
the survival time of mice could be increased by Sinupret® tablets
therapeutically (März et al. 1999) and by Sinupret® drops if given
prophylactically (Schmolz et al. 2001).