A Cochrane systemic review suggested that resin based fissure sealants are effective in preventing dental caries in pits and fissure surfaces of children and adolescent. In this review of 16 trials found that first permanent molar teeth sealed with resin-based seal- ant had 78% less caries on occlusal surfaces after 2 years and 60% less after 4–4.5 years compared to unsealed molars.16 Present study findings are in line with the review in such a way that in 92 % of molars, fissure sealant completely or partially retained over period of five years. However, in 8% of molars, fissure sealants were lost over the same period of time.