Each patient fasted for a minimum of six hours.
Thereafter, gastroscopy was performed using an
Olympus gastroscope (Olympus Medical Systems
Corp, Tokyo, Japan). Six gastric mucosal biopsies were
obtained from each patient; three from the antrum and
three from the gastric body. Two biopsy specimens (one
each from the antrum and gastric body) were each used
for the HpOne test, CLO test and histology (Fig. 1). A
co-investigator interpreted the results of the HpOne and
CLO tests at 30 minutes, 60 minutes and 24 hours after
commencement of the tests. The tests were considered
positive when either specimen recorded a positive result.
An experienced senior pathologist evaluated the biopsy
specimens and provided the histological fndings.