The seed parts were separated, dried and grounded into fine powder using a blender. Extractions were performed in a Soxhlet apparatus with methanol. The extract were concentrated by rotary
evaporator and then dried in very low pressure. The dried extracts were stored at -2oC. A stock of 10 mg of extract was prepared in 1mL dimethyl sulfoxide (DMSO) and
was filtered using 0.22mm syringe filter. The percentage of DMSO in the experiment kept below 0.5).