Ayurveda is a 5 000 years old healing tradition rooted in ancient Indian culture. This vast body of healing knowledge -sometimes referred to as “Mother of all healing”- has recently come to the attention of Western medical researchers on seeking novel therapeutic compounds due to concerns over more invasive, expensive and potentially toxic main stream practices. According to World Health Organization, about 80% of world population rely chiefly on plant based traditional medicine for their primary healthcare need[1]. Traditional healing system around the world that utilizes herbal remedies are an important resource for the discovery of modern drugs[2]. While screening a number of medicinal plants, scientist discovered one of the most revered medicinal plant i.e. Terminalia chebula (T. chebula) Retz. (Combretaceae), which exhibited a number of medicinal activities due to the presence of a large number of different types of phytoconstituents. The fruit of the tree possesses diverse health benefits and has been used as traditional medicine for household remedy against various human ailments since antiquity[3]–[5]. T. chebula has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a cynosure of modern medicine. The observed health benefits may be credited to the presence of the various phytochemicals like polyphenols, terpenes, anthocyanins, flavonoids, alkaloids and glycosides. The purpose of this review is to gather together the available published information on pharmacological and phytochemical analysis of the extracts and some of the isolated compounds of this plant as well as their toxic effects in a bid to highlighting the importance of this untapped resource in the fight against the human diseases.
Ayurveda is a 5 000 years old healing tradition rooted in ancient Indian culture. This vast body of healing knowledge -sometimes referred to as “Mother of all healing”- has recently come to the attention of Western medical researchers on seeking novel therapeutic compounds due to concerns over more invasive, expensive and potentially toxic main stream practices. According to World Health Organization, about 80% of world population rely chiefly on plant based traditional medicine for their primary healthcare need[1]. Traditional healing system around the world that utilizes herbal remedies are an important resource for the discovery of modern drugs[2]. While screening a number of medicinal plants, scientist discovered one of the most revered medicinal plant i.e. Terminalia chebula (T. chebula) Retz. (Combretaceae), which exhibited a number of medicinal activities due to the presence of a large number of different types of phytoconstituents. The fruit of the tree possesses diverse health benefits and has been used as traditional medicine for household remedy against various human ailments since antiquity[3]–[5]. T. chebula has been extensively used in Ayurveda, Unani and Homoeopathic medicine and has become a cynosure of modern medicine. The observed health benefits may be credited to the presence of the various phytochemicals like polyphenols, terpenes, anthocyanins, flavonoids, alkaloids and glycosides. The purpose of this review is to gather together the available published information on pharmacological and phytochemical analysis of the extracts and some of the isolated compounds of this plant as well as their toxic effects in a bid to highlighting the importance of this untapped resource in the fight against the human diseases.
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