This combination of file images shows clockwise from upper right: NBA player Lebron James, Singer Justin Bieber, New Jersey Governor Chris Christie, media proprietor Oprah Winfrey, singer Jennifer Lopez and singer Lady Gaga. These are just a handful of celebrities who have taken the "ALS Ice Bucket Challenge. The "ALS Ice Bucket Challenge" to raise donations for the ALS Association, which fights against Lou Gehrig's disease – or Lou Gehrig's disease, or Amyotrophic Lateral Sclerosis (ALS) – a neurodegenerative disease. AFP PHOTO / FILES