Years later, a deadly disease were spreading around Krung Sri Ayutthaya where large number of general population felled sick and were unable to find any antidotes to contain the diseases, the King was very concerned for his subjects well-being and with infections that are transmitting in the kingdom, he urgently summons all the court officials to discussed what are their contingency plans in containing the diseases. Out of a sudden, the king recalls Phra Sameramo “ Phrarajchamuni Sameeram Khunupanachan “ and instantly ordered Srithanonchai Sangkhakiri to invite Phrarajchamuni Sameeram Khunupanachan to the palace to meet him, when Phrarajchamuni Sameeram Khunupanachan was inform and learned of the contagious diseases he started to reciting the Buddhist sutra by holding onto a very huge earthen vessel that contained the lustral waters, thereafter he set off to the township and begin to distribute and splattered the holy waters around Krung Sri Ayutthaya and the outer vicinity. Eventually the whole epidemics decreased gradually. After learning the miracles of lustral waters produced by Phrarajchamuni Sameeram Khunupanachan, the Kings begin to have more faith on Phrarajchamuni Sameeram Khunupanachan and publicised that whatever request or essential items Phrarajchamuni Sameeram Khunupanachan required, he promised that all his requests will be deliver and be make available to him.