Grouping of Animals, Drug Administration and Collection of Blood Samples
Twenty-four male healthy rabbits were divided into the two groups: Group A and B. Group A comprised of 12 normal rabbits. Eight days before the collection of blood samples for analysis, group B was rendered diabetic by giving intravenously alloxan 150 mg/kg (in 10% isotonic saline) body weight. Six (Group A1) of the normal rabbits (Group A) were given garlic extract 250 mg/kg body weight, 300 mg/kg body weight and 350 mg/ /kg body weight with an interval of 72 h, whereas six normal rabbits (Group A2) of group A2 were given 250 mg/kg body weight, 375 mg/kg body weight and 500 mg/kg body weight of metformin with the same interval of 72 h. Similarly, six (Group B1) diabetic rabbits (Group B) were given the same doses of garlic extract as administered to group Al and six diabetic rabbits (Group B2) from group B were given the same doses of metformin as were given to the rabbits in group A2 in the same time interval.
Grouping of Animals, Drug Administration and Collection of Blood Samples Twenty-four male healthy rabbits were divided into the two groups: Group A and B. Group A comprised of 12 normal rabbits. Eight days before the collection of blood samples for analysis, group B was rendered diabetic by giving intravenously alloxan 150 mg/kg (in 10% isotonic saline) body weight. Six (Group A1) of the normal rabbits (Group A) were given garlic extract 250 mg/kg body weight, 300 mg/kg body weight and 350 mg/ /kg body weight with an interval of 72 h, whereas six normal rabbits (Group A2) of group A2 were given 250 mg/kg body weight, 375 mg/kg body weight and 500 mg/kg body weight of metformin with the same interval of 72 h. Similarly, six (Group B1) diabetic rabbits (Group B) were given the same doses of garlic extract as administered to group Al and six diabetic rabbits (Group B2) from group B were given the same doses of metformin as were given to the rabbits in group A2 in the same time interval.
การแปล กรุณารอสักครู่..
