The study population consisted of 14 230 ECD kidney transplant
recipient pairs reported to the SRTR between January,
1995 and October, 2009. The median difference in
CIT was 5 h (25th percentile = 3 h, 75th percentile = 9 h).
Donor characteristics of the study population included
10.0% African American and 51.9% female; 85.6% had
a cerebrovascular cause of death, 66.8% had a history of
hypertension and 10.6% had a history of diabetes.
Compared to donors that were excluded due to equivalent
CIT, there were no statistically significant differences
among any of these characteristics. The DGF incidence
in the paired kidneys with the same CIT time was similar
(32%), to the lower CIT group (31%) and significantly
lower than the higher CIT group (35%). Overall graft survival
(8 year = 40%) was slightly lower compared to both
the lower (42%) and higher (41%) CIT group and acute rejection
at 1 year was lower in the same CIT group (14%)
compared to the lower and higher CIT groups which were
both 18%.
The relevant characteristics of recipients are presented
in Table 1. The shorter CIT group comprised significantly
higher proportions of pre-emptive recipients and a lower
proportion of kidneys from nonlocal donors and fewer 0
HLA mismatched transplants compared to the long CIT
group; the two groups were similar in terms of the other
characteristics evaluated.