The aim of this study was to optimize an analytical method
which employs MSPD and determination by GC–MS for the
extraction of atrazine, clomazone, dimethoate, fenitrothion, fipronil,
malathion and tebuconazole from fish liver and crab hepatopancreas
samples. Some parameters that affect the efficiency of
the extraction were evaluated. The research aimed at reusing
packing from C18 cartridges generated by the SPE technique. The
method is environmentally friendly and minimizes costs regarding
the sorbent, without affecting its precision and its accuracy. In
addition, the use of a vortex instead of a vacuum manifold for the
elution step enabled the analyst to be less exposed to the solvent
and sample handling