Immediate effects of glucomannan on glucose-induced changes of ghrelin and leptin in type 2 diabetic patients were
shown in this study.
The prandial reduction of plasma ghrelin after test meal was less pronounced in diabetic patients when
compared to non-diabetic individuals [3] Thus, the greatest reduction of ghrelin and longer prandial ghrelin suppression,
if occurring after being glucomannan-primed, should be of benefit to prolong the next meal, particularly, among groups
having moderate insulin resistance.