INTRODUCTION
Unlike nosocomial systemic candidiasis, which is a common
problem in neonatal intensive care units worldwide, congenital
candidiasis is a very rare disease reported both in term and preterm
infants, with less than 100 cases published in the medical
literature.1 The reasons that explain why the disease is so rare are
currently unknown, since even with a high incidence of Candida albicans vaginal infection of 10–35% during pregnancy.2 It is
estimated than less than 1% of women develop chorioamnionitis,
which is considered the mechanism for fetal infection.3 Candida
chorioamnioitis has been associated more frequently with preterm
labor and intrauterine fetal death than with congenital
candidiasis.4–6 Intrauterine devices and cervical cerclage are
reported as significant risk factors, especially in extremely low birth
weight infants.
INTRODUCTION
Unlike nosocomial systemic candidiasis, which is a common
problem in neonatal intensive care units worldwide, congenital
candidiasis is a very rare disease reported both in term and preterm
infants, with less than 100 cases published in the medical
literature.1 The reasons that explain why the disease is so rare are
currently unknown, since even with a high incidence of Candida albicans vaginal infection of 10–35% during pregnancy.2 It is
estimated than less than 1% of women develop chorioamnionitis,
which is considered the mechanism for fetal infection.3 Candida
chorioamnioitis has been associated more frequently with preterm
labor and intrauterine fetal death than with congenital
candidiasis.4–6 Intrauterine devices and cervical cerclage are
reported as significant risk factors, especially in extremely low birth
weight infants.
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