Traditionally, Caciocavallo cheese is produced from raw milk without the addition of a starter culture even if, during the last 2 decades, the use of pasteurized milk and starter cultures has been introduced into commercial practice to standardize cheese quality. Dif-ferent types of Caciocavallo cheeses can be produced with different manufacturing technologies, varying the kind of milk used and its thermal treatment, the use of starter culture and its composition, and the curd and cheese ripening conditions (Niro et al., 2012), leading to products characterized by different traits