The ozone layer shields the Earth from the harmful effects of ultraviolet radiation from the sun. With the depletion of the ozone layer, more UV radiation can reach the Earth’s surface. Long term effects of UV exposure will cause skin cancer and cataract in humans. Plants and animals will be harmed too.
Therefore, we should replace CFCs with other substance that are not harmful. With the signing of Montreal Protocol, the production and use of CFCs will be phased out in stages.