Morphologic changes
After 72h, AGS and also L929 cells with low concentrations (125 and 250 µg/ml) of extract in sense of morphology were very similar to the control. Morphological effects of the extract on both cells started at concentration of 500µg/ml. A complete response from the extract was seen on both cells at concentrations 750 and 1000 µg/ml, so that cells appeared as round and suspended with increase granulation of cytoplasm when compared to the control. The granulation of cytoplasm also was seen on times 24 and 48 h after addition of extract. However, this effect was lower than 72h (data not shown).