The series has been well received in Japan, with the anime adaptation ranking in the top twenty in Animage's polls between 1996 until 2000, where it dropped below the top twenty. In the Japanese TV anime ranking, Detective Conan often ranked the top six. It has even been used as a mascot to promote citizens to follow the law. The English adaption has not been as equally popular as in Japan, and has been criticized for the name changes.
The manga is a huge success and it is continued to be published. It won the prestigious Shogakukan Manga Award for the shōnen category in 2000. Some of its volumes appear on the lists of best-selling manga.
The series is successful in Asia and Europe, where some countries translated most of the episodes and volumes. Due to the high popularity DC is re-broadcasting in many countries after the original premieres.
Although popular in many other countries, Case Closed was not as successful in the US, most likely due to poor advertising, name changes, and script changes. Due to this, the "Case Closed" version was cancelled at only 130 episodes. However, the manga is still released by VIZ media.