The issue of selecting the molecules fitting in the field of self-medication is non-trivial. This is partly due to the absence of an explicit ‘self-medication’ indication in most drug data and knowledge bases. In fact, we consider that being an OTC drug is not a sufficient condition to belong to our self-medication category. For instance, in France, some drugs belong to the family of OTC products but we do not recommend them for self-medication due to some of their properties, e.g., contraindications or unadapted therapeutic classes.