In herbal medicine, crude plant extracts are traditionally
used by the population for the treatment of diseases, including
infectious diseases. Although their efficacy and mechanisms of
action have not been tested scientifically in most cases, these
simple medicinal preparations often mediate beneficial responses
due to their active chemical constituents (Barnes
et al., 2007). A. majus at pH (6.8) was found to be very effective
against S. aureus, E. coli and P. vulgaris with zone of inhibition
14 mm, 12.5 mm and 12 mm with protein concentration
(2.73 lg). A. ascolinicum at pH (5.8) against E. coli and P. vulgaris
with zone of inhibition 17 mm, protein concentration
(2.73 lg) and the least activity was found in P. aeruginosa with
zone of inhibition 7.5 mm with the same protein concentration (2.73 lg). The consonance of the work was done using
CH2Cl2/MeOH (1:1) extract, (Zellagui et al., 2011) the extract
exhibited varying degrees of antibacterial activity depending
on the dose used. A. majus is used for the treatment of
leukoderma and psoriasis (Kumar, 1998).