A wild-typecrygene has a low G+C content, many po-tential polyadenylation sites , and numerous ATTTA se-quences. It is expressed poorly in plants as a full length or as atruncated gene. A synthetic type cry gene was designed by
mutagenesis with plant preferred codons, low A+T per-centage and increased G+C concentration. This synthetic
gene got expressed 500 times more than wild type in Trans-genic tobacco and showed complete protection toward beet
aminopeptidase-N(APN), aGPI-anchoredalkalinephosphatase (ALP) anda270kDaglycoconjugate.Alkalinephosphatasehas
also been proposed as Cry1Ac receptor.List of receptors for Cry1halotypeprotoxins insomeorganismsaregiveninTable3.