It should be noted that extraction using organic solvent might
lead to product contaminated with residual solvent. Considering
the negative effect of solvent extraction, some efforts have been
made to extract the natural product using SC-CO2. Aside from
solving any possible contamination issues, the method is advantageous
as it uses CO2 which is an inexpensive and high purity
substance, easy to remove from the extracts, is non-flammable and
non-harmful to human