Epidemiologic studies of gold miners in South Africa, granite quarry workers in Hong Kong, metal miners in Colorado, and coal miners in Scotland have shown that chronic silicosis may develop or progress even after occupational exposure to silica has been discontinued [Hessel et al. 1988; Hnizdo and Sluis-Cremer 1993; Ng et al. 1987; Kreiss and Zhen 1996; Miller et al. 1998]. Therefore, removing a worker from exposure after diagnosis does not guarantee that silicosis or silica-related disease will stop progressing or that an impaired worker’s condition will stabilize. Treatment of silicosis may include use of bronchodilators (medications to open the airways) or supplemental oxygen. Once disease is detected, it is important to protect the lungs against respiratory infections, therefore a doctor may recommend vaccinations to prevent influenza and pneumonia. In some cases of severe disease, a lung transplant may be recommended. Prognosis depends on the length and level of exposure to respirable quartz dust. There is no cure for this lung disease and it cannot be reversed. Consequently, control technologies must be implemented in an effort to prevent the development of the disease. As an added measure of protection, a respirator program can be implemented for workers exposed to silica dust.