CKD is also considered as an independent risk factor for
bleeding, and, therefore, warfarin use in patients who have
severe CKD could increase the risk for bleeding.2 Moreover,
in patients with AF undergoing hemodialysis, it is routine
practice to administer heparin, which could also increase the
risk for bleeding.15
Current observational studies on warfarin use and the
risk for stroke and bleeding in patients with AF undergoing
dialysis present conflicting results.1,8,16,17 Globally, because
of a lack of evidence from randomized, controlled trials, AF