In this study, we evaluated the phenolic profile, antioxidant and anti-cholinesterase potential of different
extracts from wild plants andin vitro cultures ofLavandula viridisL’Hér. The HPLC–DAD analysis allowed
the identification and quantification of 3-O-caffeoylquinic, 4-O-caffeoylquinic, 5-O-caffeoylquinic and
rosmarinic acids, and luteolin and pinocembrin. Water/ethanol extract fromin vitro cultures contained
the highest amount of the identified phenolic compounds (51652.92 mg/kg). To investigate the antioxidant activity we used Trolox equivalent antioxidant capacity, oxygen radical absorbance capacity, Fe
2+
chelation activity and the inhibition of Fe
2+
-induced lipid peroxidation in mouse brain homogenates
(in vitro). Overall, all the extracts from both wild plants andin vitrocultures exhibited ability to scavenge
free radicals, to chelate Fe
2+and to protect against lipid peroxidation. In addition, the extracts fromL. viridiswere active in inhibiting both acetylcholinesterase and butyrylcholinesterase (Ellman’s method). Our
findings suggest thatL. viridis in vitrocultures represent a promising alternative for the production of
active metabolites with antioxidant and anti-cholinesterase activity.
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