Although Colgate Total triclosan dentifrice is an FDA approved anti-gingivitis therapy, we have shown that not all persons with gingivitis have a favorable clinical response. Additionally, we demonstrated that switching triclosan/copolymer users with residual gingivitis from a 0.3% triclosan/ copolymer dentifrice to a 0.454% stannous fluoride dentifrice resulted in a greater reduction in gingival inflammation and bleeding compared to maintaining the use of the 0.3% triclosan/ copolymer dentifrice. The results of this study suggest that patients with gingivitis who have not improved with use of a triclosan-containing dentifrice may show improvement with a 0.454% stannous fluoride containing dentifrice.