All the cholesterol concentrations, including the total cholesterol,
HDL-C and LDL-C were reduced by high levels of dietary FPH in the present study. The cholesterol-lowering effect of FPH diets (diets with
10% or 22% FPH) compared to casein diets have previously been observed
in rodents and it might be attributed to decreased intestinal absorption
concomitant with increased hepatic excretion of cholesterol
and bile (Hosomi et al., 2011; Liaset et al., 2011). However, in the fish
study on Atlantic salmon, 15% FPH replacing fish meal in the diet did
not affect the liver cholesterol concentration compared to the diet
with 0% FPH (Espe et al., 2012a). Both the species and dietary level of
FPH could influence the effects of dietary FPH on cholesterol
metabolism.