The two main objectives of the present study were: (i) to evaluate
the use of both the constant Reynolds number and the constant
impeller tip speed as scale-up methodologies under
laboratory conditions for the step-wise scale-up process from
100 mL shaken flask to 10 L stirred-tank bioreactor, considering
whether an increase in the bioethanol yield can be achieved, and
(ii) to validate the kinetic models applied for better describing
the behaviors of Escherichia coli KO11 during ethanol fermentation
from rice hulls hydrolysate.